Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 15/20 | 0.54 |
| ▸ | CCNH | P51946 | 15/20 | 0.54 |
| ▸ | MNAT1 | P51948 | 13/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.54 |
| ▸ | CDK2 | P24941 | 12/20 | 0.54 |
| ▸ | CCNK | O75909 | 12/20 | 0.54 |
| ▸ | CDK12 | Q9NYV4 | 12/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.54 |
| ▸ | CDK9 | P50750 | 11/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517413 | 1.00 | CDK7 (0.54) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL21026876 | 0.84 | CDK5 (0.69) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL24839369 | 0.84 | CDK7 (0.55) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL24900503 | 0.84 | CCNK (0.48) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL30957595 | 0.84 | CCNK (0.48) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL30957590 | 0.84 | TDO2 (0.47) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL24900493 | 0.84 | TDO2 (0.47) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL21629046 | 0.83 | CCNK (0.44) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL21178668 | 0.83 | CLK1 (0.50) | CDK7CCNHMNAT1CCNE1CDK2 | |
| SCHEMBL21184587 | 0.83 | CCNK (0.42) | CDK7CCNHMNAT1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159533-A | Heterocyclic compounds and their use | 艾森医药有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2023040998-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-23 | — | — | WO | disclosed |
| CN-108276382-B | Cyclin-dependent kinase inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |