Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | SI | P14410 | 4/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901454 | 0.76 | KDM4E (0.40) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL30694806 | 0.73 | KDM4E (0.41) | KDM4ETDP1HRH4SMN1; SMN2 | |
| SCHEMBL15968924 | 0.73 | KDM4E (0.41) | KDM4ETDP1HRH4SMN1; SMN2 | |
| SCHEMBL24901457 | 0.70 | HTR2A (0.30) | — | |
| SCHEMBL24901455 | 0.69 | HAO1 (0.35) | LMNAHRH4SMN1; SMN2 | |
| SCHEMBL24901535 | 0.68 | MAPT (0.32) | — | |
| SCHEMBL24901480 | 0.68 | MAPT (0.32) | — | |
| SCHEMBL29419589 | 0.67 | CA2 (0.56) | KDM4ETDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20509 | 0.67 | CA2 (0.56) | KDM4ETDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4573180 | 0.67 | KDM4E (0.41) | KDM4ETDP1HRH4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |