SCHEMBL24901480

SCHEMBL24901480

CC(C)[Si](OCC(F)(F)Oc1c(F)cc(Br)cc1Cl)(C(C)C)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24901535 0.86 MAPT (0.32) MAPT
SCHEMBL24901476 0.75 MAPT (0.34) MAPT
SCHEMBL30756731 0.71 TRPV1 (0.33) MAPT
SCHEMBL24901703 0.68 MGAM (0.39)
SCHEMBL12144523 0.67 MAPT (0.43) MAPT
SCHEMBL16858608 0.67 MAPT (0.43) MAPT
SCHEMBL24901455 0.66 HAO1 (0.35) MAPT
SCHEMBL15271622 0.65 ACLY (0.41) MAPT
SCHEMBL24901479 0.65 GPR35 (0.38) MAPT
SCHEMBL15270576 0.63 SLC6A2 (0.33) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023286768-A1 HYDROGENATED QUINOXALINES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2023-01-19 WO disclosed