Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30756731 | 0.81 | TRPV1 (0.33) | SMN1; SMN2MAPT | |
| SCHEMBL2038046 | 0.76 | SMN1; SMN2 (0.39) | HAO1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL24901459 | 0.75 | SMN1; SMN2 (0.41) | HAO1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL17205115 | 0.73 | HAO1 (0.44) | HAO1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL29427162 | 0.72 | GPR3 (0.45) | HAO1LMNAALOX15SMN1; SMN2MAPT | |
| SCHEMBL1221631 | 0.72 | GPR3 (0.45) | HAO1LMNAALOX15SMN1; SMN2MAPT | |
| SCHEMBL24901535 | 0.72 | MAPT (0.32) | MAPT | |
| SCHEMBL24901703 | 0.69 | MGAM (0.39) | LMNASMN1; SMN2HRH4 | |
| SCHEMBL506056 | 0.69 | PARP1 (0.33) | HAO1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL24901457 | 0.69 | HTR2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |