Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901894 | 0.86 | CYP4F2 (0.51) | NR4A2ADAM17MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL24901899 | 0.80 | MAOB (0.52) | NR4A2ADAM17MAOBKDM4EALDH1A1 | |
| SCHEMBL24901890 | 0.79 | ADAM17 (0.49) | NR4A2ADAM17MAOBKMT2A | |
| SCHEMBL2453935 | 0.78 | DGAT1 (0.49) | KMT2ASMN1; SMN2PKM | |
| SCHEMBL10083334 | 0.78 | MAOB (0.57) | NR4A2ADAM17MAOBFFAR1KMT2A | |
| SCHEMBL17817801 | 0.78 | NR4A2 (0.50) | NR4A2ADAM17MAOBFFAR1KMT2A | |
| SCHEMBL7810973 | 0.75 | AKR1C1 (0.55) | NR4A2ADAM17MAOBKMT2ASMPD1 | |
| SCHEMBL7807417 | 0.73 | ADAM17 (0.57) | NR4A2ADAM17MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL6584414 | 0.73 | CYP4F2 (0.51) | NR4A2ADAM17MAOBCYP4F2CYP4A11 | |
| SCHEMBL2959082 | 0.73 | CYP4F2 (0.51) | NR4A2ADAM17MAOBCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001237-A1 | GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF | Hepagene Therapeutics (HK) Limited (CN) | 2023-01-26 | — | — | WO | disclosed |