Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901894 | 0.80 | CYP4F2 (0.51) | MAOBMAOABCHENR4A2ADAM17 | |
| SCHEMBL24901900 | 0.80 | NR4A2 (0.50) | MAOBMAOANR4A2ADAM17KDM4E | |
| SCHEMBL7582234 | 0.77 | ALOX5 (0.62) | MAOBMAOACCNB2CDK1CDK4 | |
| SCHEMBL24901890 | 0.76 | ADAM17 (0.49) | MAOBBCHENR4A2ADAM17 | |
| SCHEMBL25155645 | 0.75 | MAOB (0.57) | MAOBMAOACCNB2CDK1CDK4 | |
| SCHEMBL2447393 | 0.74 | PNMT (0.54) | MAOBMAOAALDH1A1 | |
| SCHEMBL10083334 | 0.74 | MAOB (0.57) | MAOBMAOANR4A2ADAM17KDM4E | |
| SCHEMBL6584414 | 0.72 | CYP4F2 (0.51) | MAOBMAOABCHENR4A2ADAM17 | |
| SCHEMBL2959082 | 0.72 | CYP4F2 (0.51) | MAOBMAOABCHENR4A2ADAM17 | |
| SCHEMBL25838752 | 0.72 | OPRD1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001237-A1 | GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF | Hepagene Therapeutics (HK) Limited (CN) | 2023-01-26 | — | — | WO | disclosed |