SCHEMBL24901946

SCHEMBL24901946

COC(=O)c1cc(C)c(N)c(NC[C@@H]2CCO2)c1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.43
KMT2A Q03164 4/20 0.41
HPGD P15428 6/20 0.39
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 2/20 0.38
HSD17B10 Q99714 1/20 0.38
HCAR3 P49019 1/20 0.38
TDO2 P48775 1/20 0.38
ATAD2 Q6PL18 1/20 0.38
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30232663 1.00 PTGER4 (0.43) PTGER4KMT2AHPGDALDH1A1SMN1; SMN2
SCHEMBL29640531 0.88 KMT2A (0.40) PTGER4KMT2AHPGDALDH1A1SMN1; SMN2
SCHEMBL31463429 0.88 KMT2A (0.40) PTGER4KMT2AHPGDALDH1A1SMN1; SMN2
SCHEMBL29640529 0.88 KMT2A (0.40) PTGER4KMT2AHPGDALDH1A1SMN1; SMN2
SCHEMBL24455263 0.88 KMT2A (0.40) PTGER4KMT2AHPGDALDH1A1SMN1; SMN2
SCHEMBL25279173 0.88 KMT2A (0.40) PTGER4KMT2AHPGDALDH1A1SMN1; SMN2
SCHEMBL25404705 0.88 KMT2A (0.40) PTGER4KMT2AHPGDALDH1A1SMN1; SMN2
SCHEMBL24960037 0.88 ALDH1A1 (0.41) PTGER4KMT2AHPGDALDH1A1KDM4E
SCHEMBL29159913 0.88 ALDH1A1 (0.41) PTGER4KMT2AHPGDALDH1A1KDM4E
SCHEMBL27176929 0.88 KDM4E (0.42) PTGER4KMT2AHPGDALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067630-A1 ARYL ETHER-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS GLP1R AGONISTS MINDRANK AI LTD. (CN) 2024-02-29 US disclosed
US-20240067630-A1 ARYL ETHER-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS GLP1R AGONISTS MINDRANK AI LTD. (CN) 2024-02-29 US disclosed
WO-2023001237-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF Hepagene Therapeutics (HK) Limited (CN) 2023-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067630-A1 ARYL ETHER-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS GLP1R AGONISTS GLP1R, GIPR, GCGR PTGER4 1906/4885KMT2A 1759/4885HPGD 2273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.