Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640531 | 1.00 | KMT2A (0.40) | KMT2AALDH1A1SMN1; SMN2LMNAALOX12 | |
| SCHEMBL24455263 | 1.00 | KMT2A (0.40) | KMT2AALDH1A1SMN1; SMN2LMNAALOX12 | |
| SCHEMBL30232663 | 0.88 | PTGER4 (0.43) | KMT2AALDH1A1SMN1; SMN2PTGER4HPGD | |
| SCHEMBL24901946 | 0.88 | PTGER4 (0.43) | KMT2AALDH1A1SMN1; SMN2PTGER4HPGD | |
| SCHEMBL25279173 | 0.86 | KMT2A (0.40) | KMT2AALDH1A1SMN1; SMN2PTGER4HPGD | |
| SCHEMBL31463429 | 0.86 | KMT2A (0.40) | KMT2AALDH1A1SMN1; SMN2PTGER4HPGD | |
| SCHEMBL29159913 | 0.86 | ALDH1A1 (0.41) | KMT2AALDH1A1PTGER4HPGDKDM4E | |
| SCHEMBL25404705 | 0.86 | KMT2A (0.40) | KMT2AALDH1A1SMN1; SMN2PTGER4HPGD | |
| SCHEMBL24960037 | 0.86 | ALDH1A1 (0.41) | KMT2AALDH1A1PTGER4HPGDKDM4E | |
| SCHEMBL27176929 | 0.86 | KDM4E (0.42) | KMT2AALDH1A1SMN1; SMN2PTGER4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473271-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2025-11-18 | — | — | US | disclosed |
| US-20240199580-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2024-06-20 | — | — | US | disclosed |
| US-11851419-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2023-12-26 | — | — | US | disclosed |
| EP-4247804-A1 | POLYHETEROCYCLIC GLP-1 R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022109182-A9 | POLYHETEROCYCLIC GLP-1 R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-08 | — | — | WO | disclosed |
| US-20220177449-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2022-06-09 | — | — | US | disclosed |
| WO-2022109182-A1 | POLYHETEROCYCLIC GLP-1 R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177449-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | KMT2A 3870/4885ALDH1A1 3556/4885SMN1; SMN2 1956/4885 |
| US-11851419-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | KMT2A 3870/4885ALDH1A1 3556/4885SMN1; SMN2 1956/4885 |
| US-12473271-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | KMT2A 3870/4885ALDH1A1 3556/4885SMN1; SMN2 1956/4885 |
| US-20240199580-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | KMT2A 3870/4885ALDH1A1 3556/4885SMN1; SMN2 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.