Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23254707 | 0.90 | HPGD (0.63) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL18232444 | 0.87 | HPGD (0.68) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL12090047 | 0.86 | HPGD (0.67) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL26078960 | 0.86 | HPGD (0.67) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL104793 | 0.85 | HPGD (0.70) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL12920005 | 0.85 | HPGD (0.75) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL18232446 | 0.84 | HPGD (0.65) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL13165401 | 0.84 | ALDH1A1 (0.63) | RAB9ANPC1ALDH1A1HDAC3L3MBTL1 | |
| SCHEMBL18232447 | 0.84 | HPGD (0.68) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL13577935 | 0.84 | HPGD (0.68) | HPGDRAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230018460-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | Infex Therapeutics Limited (GB) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230018460-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | CPN1, CMBL, ALDH7A1 | HPGD 900/4885RAB9A 3357/4885NPC1 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.