Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.45 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24904343 | 0.84 | HPGD (0.58) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL12774556 | 0.83 | KDM4E (0.66) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL15296601 | 0.81 | TDP1 (0.57) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL12089930 | 0.80 | RAB9A (0.58) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL14441183 | 0.80 | RAB9A (0.58) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL105171 | 0.80 | HDAC6 (0.59) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL104304 | 0.79 | RAB9A (0.61) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL10154034 | 0.79 | GPR139 (0.61) | SMN1; SMN2MEN1KMT2AHPGDGPR139 | |
| SCHEMBL25442217 | 0.79 | HPGD (0.60) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL12774559 | 0.79 | KDM4E (0.60) | RAB9ASMN1; SMN2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230018460-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | Infex Therapeutics Limited (GB) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230018460-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | CPN1, CMBL, ALDH7A1 | RAB9A 3357/4885SMN1; SMN2 2657/4885MEN1 2618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.