SCHEMBL2490553

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2491739	0.87	KDM4E (0.41)	PIK3CDALDH1A1CNR1CNR2BCHE
	SCHEMBL2492562	0.85	ALDH1A1 (0.39)	PIK3CDALDH1A1BCHEACHEKDM4E
	SCHEMBL2494943	0.85	MAOB (0.33)	ALDH1A1KDM4EHPGDHSD17B10MAPT
	SCHEMBL2489056	0.85	MGAM (0.34)	—
	SCHEMBL2490551	0.82	SMN1; SMN2 (0.35)	MAPK1PIK3CDALDH1A1BCHEACHE
	SCHEMBL2492433	0.81	ALDH1A1 (0.39)	PIK3CDALDH1A1ADORA2AKDM4EHPGD
	SCHEMBL12175914	0.80	CD274 (0.47)	ALDH1A1CNR2KDM4ELMNAHPGD
	SCHEMBL1136308	0.79	MAOB (0.39)	HPGDMAPTBCL9CTNNB1
	SCHEMBL2531189	0.79	CHKA (0.44)	PIK3CDALDH1A1KDM4EHPGDHSD17B10
	SCHEMBL2492254	0.77	MAOB (0.37)	BCL9CTNNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.