SCHEMBL2491739

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2492433	0.90	ALDH1A1 (0.39)	KDM4ETP53PIK3CDIL6TLR7
	SCHEMBL2492562	0.88	ALDH1A1 (0.39)	KDM4ETP53PIK3CDALDH1A1BCHE
	SCHEMBL2531189	0.87	CHKA (0.44)	KDM4EPIK3CDIL6TLR7ALDH1A1
	SCHEMBL2490553	0.87	MAPK1 (0.41)	KDM4ESMN1; SMN2TP53PIK3CDCNR1
	SCHEMBL2490551	0.87	SMN1; SMN2 (0.35)	KDM4EHIF1ASMN1; SMN2TP53PIK3CD
	SCHEMBL2488943	0.87	MAPT (0.40)	SMN1; SMN2TP53L3MBTL1
	SCHEMBL1136308	0.84	MAOB (0.39)	L3MBTL1
	SCHEMBL2491400	0.84	LMNA (0.42)	KDM4EALDH1A1PARP1L3MBTL1
	SCHEMBL2585571	0.83	HDAC1 (0.38)	SMN1; SMN2TP53L3MBTL1
	SCHEMBL2490987	0.83	DRD4 (0.36)	KDM4ESMN1; SMN2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.