Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711806 | 0.85 | RAB9A (0.73) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL31692494 | 0.82 | HTT (0.64) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| Bicarbonate SCHEMBL19664773 | 0.82 | RAB9A (0.69) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL4604094 | 0.80 | KDM4E (0.57) | ALDH1A1KMT2ARAB9AMEN1GAA | |
| SCHEMBL28592805 | 0.79 | CYP2C19 (0.64) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL13716462 | 0.78 | RAB9A (0.64) | ALDH1A1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL1322743 | 0.78 | HTT (0.71) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL29419622 | 0.78 | HTT (0.71) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL3717777 | 0.77 | PDK1 (0.55) | ALDH1A1KMT2ARAB9AMEN1PDK1 | |
| SCHEMBL28895412 | 0.76 | HTT (0.54) | ALDH1A1NPC1RAB9APDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230014962-A1 | Quinoline compound and use thereof | SKYRUN PHARMA CO LTD (CN) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230014962-A1 | Quinoline compound and use thereof | FGFR4, FGFR1, FGFR3 | ALDH1A1 1995/4885KMT2A 1507/4885NPC1 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.