Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419622 | 0.86 | HTT (0.71) | HTTRAB9AS1PR1PDK1PDK2 | |
| SCHEMBL1322743 | 0.86 | HTT (0.71) | HTTRAB9AS1PR1PDK1PDK2 | |
| SCHEMBL21750908 | 0.81 | RAB9A (0.76) | HTTRAB9AS1PR1NPC1ALDH1A1 | |
| SCHEMBL21750902 | 0.81 | RAB9A (0.72) | HTTRAB9AS1PR1NPC1CXCR2 | |
| SCHEMBL21750960 | 0.79 | RAB9A (0.74) | HTTRAB9AS1PR1MAPK1NPC1 | |
| SCHEMBL3717777 | 0.77 | PDK1 (0.55) | HTTRAB9AS1PR1PDK1PDK2 | |
| SCHEMBL24906148 | 0.76 | ALDH1A1 (0.57) | HTTRAB9AS1PR1PDK1PDK2 | |
| SCHEMBL29264920 | 0.75 | S1PR1 (0.48) | HTTRAB9AS1PR1PDK1PDK2 | |
| SCHEMBL21750979 | 0.75 | MAOA (0.61) | HTTRAB9ATRPV1MAPK1NPC1 | |
| SCHEMBL29757943 | 0.75 | MAOA (0.61) | HTTRAB9ATRPV1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107305202-B | HPLC method for analyzing impurities of levovatinib mesylate and preparation thereof and application of impurities as reference standard | 北京睿创康泰医药研究院有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-107305202-B | HPLC method for analyzing impurities of levovatinib mesylate and preparation thereof and application of impurities as reference standard | 北京睿创康泰医药研究院有限公司 | 2020-04-17 | — | — | CN | disclosed |