Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 8/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.31 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | IL1B | P01584 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24758133 | 0.91 | CHRM2 (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL30141508 | 0.88 | CHRM2 (0.31) | KDM4ERECQLCHRM2CHRM1CHRM3 | |
| SCHEMBL24906284 | 0.85 | KDM4E (0.35) | KDM4ERECQLCCR1LMNA | |
| SCHEMBL24906271 | 0.83 | GAA (0.32) | AADATLMNA | |
| SCHEMBL27243066 | 0.83 | CHRM2 (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL27243076 | 0.83 | CHRM2 (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL24757758 | 0.83 | CHRM2 (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL24757255 | 0.81 | RXRA (0.34) | KDM4ERECQLLMNATSHRNPSR1 | |
| SCHEMBL24757761 | 0.79 | CRHR1 (0.31) | — | |
| SCHEMBL24906247 | 0.79 | CRHR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025025-A1 | SUBSTITUTED PYRAZOLE AMIDES | GRUENENTHAL GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025025-A1 | SUBSTITUTED PYRAZOLE AMIDES | SCN8A, SCN1A, SCN7A | KDM4E 2803/4885RECQL 3104/4885CCR1 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.