Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24757255 | 0.93 | RXRA (0.34) | LMNANR1H4RXRARXRBRXRG | |
| SCHEMBL27243066 | 0.92 | CHRM2 (0.31) | CHRM2CHRM1CHRM3NR1H4RXRA | |
| SCHEMBL27243076 | 0.92 | CHRM2 (0.31) | CHRM2CHRM1CHRM3NR1H4RXRA | |
| SCHEMBL24757758 | 0.92 | CHRM2 (0.31) | CHRM2CHRM1CHRM3NR1H4RXRA | |
| SCHEMBL24906286 | 0.88 | KDM4E (0.34) | CHRM2CHRM1CHRM3LMNATSHR | |
| SCHEMBL30141501 | 0.87 | KDM4E (0.36) | LMNATSHRIDH1KDM4E | |
| SCHEMBL24906271 | 0.85 | GAA (0.32) | LMNA | |
| SCHEMBL30975999 | 0.85 | RXRA (0.33) | NR1H4RXRARXRBRXRG | |
| SCHEMBL24758133 | 0.84 | CHRM2 (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL24906247 | 0.84 | CRHR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | disclosed |