SCHEMBL2490798

SCHEMBL2490798

CCOc1ccc(C(c2ccc(OCC)cc2)c2ccc(OCC)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.70
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
LTA4H P09960 2/20 0.52
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
PARP10 Q53GL7 1/20 0.47
RELA Q04206 1/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
ADRA2A P08913 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7369820 0.91 LTA4H (0.61) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL24747416 0.89 LTA4H (0.68) NQO1TSHRTDP1LTA4HALDH1A1
SCHEMBL13523896 0.89 TDP1 (0.76) NQO1TSHRTDP1LTA4HPARP10
SCHEMBL10875478 0.86 SLC2A1 (0.65) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL9626190 0.86 SLC2A1 (0.65) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL824979 0.85 NQO1 (0.70) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL10526470 0.84 NQO1 (0.50) NQO1TSHRTDP1LTA4HKDM4E
1,4-Diethoxybenzene SCHEMBL28186701 0.84 NQO1 (1.00) NQO1TSHRTDP1LTA4HKDM4E
1,4-Diethoxybenzene SCHEMBL124015 0.84 NQO1 (1.00) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL24747419 0.83 LMNA (0.55) NQO1TSHRTDP1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10377869-B2 Precursor blend for preparing a thermoplastic polymer for a fiber-reinforced composite material and method for preparing the fiber-reinforced composite material SWANCOR INDUSTRIAL CO., LTD. (TW) 2019-08-13 US disclosed
EP-2380567-B1 MELANIN PRODUCTION INHIBITOR POLA CHEM IND INC (JP) 2019-01-16 EP disclosed
US-20170137587-A1 PRECURSOR BLEND FOR PREPARING A THERMOPLASTIC POLYMER FOR A FIBER-REINFORCED COMPOSITE MATERIAL AND METHOD FOR PREPARING THE FIBER-REINFORCED COMPOSITE MATERIAL SWANCOR ADVANCED MATERIALS CO., LTD. (CN) 2017-05-18 US disclosed
US-20170137587-A1 PRECURSOR BLEND FOR PREPARING A THERMOPLASTIC POLYMER FOR A FIBER-REINFORCED COMPOSITE MATERIAL AND METHOD FOR PREPARING THE FIBER-REINFORCED COMPOSITE MATERIAL SWANCOR ADVANCED MATERIALS CO., LTD. (CN) 2017-05-18 US disclosed
EP-3009123-A1 MELANIN PRODUCTION INHIBITOR Pola Chemical Industries Inc. (JP) 2016-04-20 EP disclosed
US-20150328107-A1 MELANIN PRODUCTION INHIBITOR POLA CHEMICAL INDUSTRIES INC. (JP) 2015-11-19 US disclosed
EP-2845587-A2 Melanin production inhibitor Pola Chemical Industries Inc. (JP) 2015-03-11 EP disclosed
US-20140363389-A1 MELANIN PRODUCTION INHIBITOR POLA CHEMICAL INDUSTRIES INC. (JP) 2014-12-11 US disclosed
US-8846012-B2 Melanin production inhibitor POLA CHEMICAL INDUSTRIES INC. (JP) 2014-09-30 US disclosed
EP-2380567-A1 MELANIN PRODUCTION INHIBITOR Pola Chemical Industries Inc. (JP) 2011-10-26 EP disclosed
US-20110243865-A1 MELANIN PRODUCTION INHIBITOR POLA CHEMICAL INDUSTRIES INC. (JP) 2011-10-06 US disclosed
US-7306898-B2 Planographic printing method and planographic printing plate precursor used therein FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
US-7306898-B2 Planographic printing method and planographic printing plate precursor used therein FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110243865-A1 MELANIN PRODUCTION INHIBITOR TYR, F12, TH NQO1 951/4885TSHR 100/4885TDP1 2051/4885
US-20150328107-A1 MELANIN PRODUCTION INHIBITOR TYR, MC1R, F12 NQO1 890/4885TSHR 75/4885TDP1 2151/4885
US-20140363389-A1 MELANIN PRODUCTION INHIBITOR TYR, F12, MC1R NQO1 850/4885TSHR 68/4885TDP1 2238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.