SCHEMBL7369820

SCHEMBL7369820

CCOc1ccc(C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.61
NQO1 P15559 1/20 0.58
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
RELA Q04206 1/20 0.55
CNR2 P34972 1/20 0.51
TAAR1 Q96RJ0 1/20 0.50
GAA P10253 2/20 0.49
TSHR P16473 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 3/20 0.47
NPC1 O15118 2/20 0.47
TP53 P04637 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2490798 0.91 NQO1 (0.70) LTA4HNQO1MEN1KMT2AL3MBTL1
SCHEMBL24747370 0.91 LTA4H (0.59) LTA4HNQO1MEN1KMT2AL3MBTL1
SCHEMBL686456 0.86 LTA4H (0.59) LTA4HNQO1MEN1KMT2AL3MBTL1
SCHEMBL645300 0.86 KMT2A (0.54) LTA4HNQO1MEN1KMT2AL3MBTL1
SCHEMBL24747421 0.85 LMNA (0.57) LTA4HMEN1KMT2AL3MBTL1CNR2
SCHEMBL11420513 0.84 LTA4H (0.57) LTA4HNQO1MEN1KMT2AL3MBTL1
SCHEMBL13098201 0.84 LTA4H (0.63) LTA4HCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL11603275 0.84 MEN1 (0.57) LTA4HNQO1MEN1KMT2AL3MBTL1
SCHEMBL14622133 0.84 LTA4H (0.57) LTA4HNQO1MEN1KMT2AL3MBTL1
SCHEMBL682834 0.82 LTA4H (0.60) LTA4HNQO1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2751087-A1 DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F]FLUOROMETHYL)TYROSINE Piramal Imaging SA (CH) 2014-07-09 EP disclosed
WO-2013001088-A1 DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F]FLUOROMETHYL) TYROSINE PIRAMAL IMAGING SA (CH) 2013-01-03 WO disclosed
EP-0749316-A4 ANTITHROMBOTIC AGENTS LILLY CO ELI (US) 1999-04-21 EP disclosed
EP-0749316-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1996-12-27 EP disclosed
WO-1995023608-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1995-09-08 WO disclosed
WO-1992011276-A1 NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1992-07-09 WO disclosed
EP-0237027-B1 6-(DISUBSTITUTED AMINO) CARBAPENAM COMPOUNDS Sanraku Incorporated (JP) 1992-06-10 EP disclosed
US-4996314-A 6-(disubstituted amino)carbapenem compounds SANRAKU INCORPORATED (JP) 1991-02-26 US disclosed
US-4812563-A ANTIBIOTICS SANRAKU INCORPORATED (JP) 1989-03-14 US disclosed
EP-0111286-B1 NOVEL BETA-LACTAM DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF Sanraku Incorporated (JP) 1988-03-02 EP disclosed
EP-0237027-A2 6-(Disubstituted amino) carbapenam compounds Sanraku Incorporated (JP) 1987-09-16 EP disclosed
US-4517127-A β-Lactam derivatives and process for production thereof SANRAKU-OCEAN CO., LTD. (JP) 1985-05-14 US disclosed
EP-0105227-A1 Process for producing beta-lactam compounds, and intermediates useful for their production Sanraku Incorporated (JP) 1984-04-11 EP disclosed
EP-0040408-A1 Beta-lactam compounds and process for production thereof SANRAKU-OCEAN CO., LTD. (JP) 1981-11-25 EP disclosed