Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31448014 | 0.86 | KEAP1 (0.62) | RAB9AKEAP1TAAR1 | |
| SCHEMBL8743573 | 0.86 | GPR139 (0.60) | RAB9ANPC1GPR139HPGDPOLB | |
| SCHEMBL11212463 | 0.85 | HPGD (0.60) | RAB9ANPC1GPR139HPGDPOLB | |
| SCHEMBL10605231 | 0.85 | POLB (0.64) | RAB9ANPC1GPR139HPGDPOLB | |
| SCHEMBL14597973 | 0.84 | NPC1 (0.58) | RAB9ANPC1GPR139HPGDPOLB | |
| SCHEMBL1520287 | 0.82 | NPC1 (0.69) | RAB9ANPC1HPGDPOLBCYP1A2 | |
| SCHEMBL30289977 | 0.81 | KMT2A (0.65) | HPGDCYP1A2ALDH1A1KEAP1TAAR1 | |
| SCHEMBL27450922 | 0.81 | KEAP1 (0.66) | RAB9AALDH1A1KEAP1 | |
| SCHEMBL2491198 | 0.81 | HPGD (0.58) | RAB9ANPC1GPR139HPGDPOLB | |
| SCHEMBL2989489 | 0.80 | NPC1 (0.71) | RAB9ANPC1GPR139HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115784914-A | Preparation method of o-chlorophenylglycine | 石家庄中硕科技有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-114685300-A | Preparation method of o-chlorophenylglycine | 抚顺顺能化工有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-116981487-A | Combination of para-aminohippuric acid (PAH) and radiolabeled complexes for the treatment of cancer | 同位素技术慕尼黑有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-114507650-B | Leucine dehydrogenase mutant and application thereof in synthesis of (S) -o-chlorophenylglycine | 浙江工业大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-217473335-U | Agitated vessel is used in preparation of adjacent chlorobenzene glycine with vibration mechanism | 石家庄中硕科技有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-114507650-A | Leucine dehydrogenase mutant and application thereof in synthesis of (S) -o-chlorophenylglycine | 浙江工业大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-214553003-U | Agitated vessel is used in preparation of o chlorobenzene glycine | 石家庄中硕科技有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-111454933-A | D-carbamoyl hydrolase mutant and application thereof in synthesis of D-aromatic amino acid | 江南大学 | 2020-07-28 | — | — | CN | disclosed |
| EP-2061764-B1 | HETEROCYCLIC DERIVATIVES BINDING TO THE PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR (PBR) | TECHNION RES & DEV FOUNDATION (IL) | 2014-07-02 | — | — | EP | disclosed |
| EP-2061764-B1 | HETEROCYCLIC DERIVATIVES BINDING TO THE PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR (PBR) | TECHNION RES & DEV FOUNDATION (IL) | 2014-07-02 | — | — | EP | disclosed |
| US-8541428-B2 | Heterocyclic derivatives, pharmaceutical compositions and methods of use thereof | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2013-09-24 | — | — | US | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| EP-0169139-B1 | HETEROCYCLIC NITROGEN COMPOUNDS, THEIR PREPARATION AND MEDICINES CONTAINING THEM | SANOFI (FR) | 1989-06-07 | — | — | EP | disclosed |
| EP-0315204-A2 | Bleaching composition | LION CORPORATION (JP) | 1989-05-10 | — | — | EP | disclosed |
| EP-0169139-A1 | Heterocyclic nitrogen compounds, their preparation and medicines containing them | SANOFI (FR) | 1986-01-22 | — | — | EP | disclosed |
| US-4359522-A | Photographic element containing a UV-filter layer | CIBA-GEIGY AG (CH) | 1982-11-16 | — | — | US | disclosed |
| US-4350692-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-09-21 | — | — | US | disclosed |
| US-4148912-A | ANTISECRETORY, ANTIULCER | SCIENCE UNION ET CIE (FR) | 1979-04-10 | — | — | US | disclosed |