Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490818 | 0.86 | RAB9A (0.63) | GPR139KEAP1POLBNPC1RAB9A | |
| SCHEMBL9491955 | 0.86 | TAS1R3 (0.57) | GPR139P2RX7TSHRERCC5FEN1 | |
| SCHEMBL23014241 | 0.84 | GPR139 (0.59) | GPR139P2RX7TSHRERCC5FEN1 | |
| SCHEMBL11570780 | 0.81 | TAS1R3 (0.55) | GPR139P2RX7TSHRERCC5FEN1 | |
| SCHEMBL4158170 | 0.81 | TAS1R3 (0.64) | GPR139P2RX7TSHRERCC5FEN1 | |
| SCHEMBL4994139 | 0.80 | ALDH1A1 (0.59) | P2RX7FEN1JAK2POLBHPGD | |
| SCHEMBL23014176 | 0.80 | P2RX7 (0.58) | GPR139P2RX7TSHRERCC5FEN1 | |
| SCHEMBL6292862 | 0.79 | TMEM97 (0.58) | GPR139P2RX7TSHRERCC5FEN1 | |
| SCHEMBL6292861 | 0.79 | P2RX7 (0.57) | GPR139P2RX7TSHRERCC5FEN1 | |
| SCHEMBL31448014 | 0.79 | KEAP1 (0.62) | TSHRKEAP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751929-A1 | ANALYSIS METHOD FOR TESTING FOR TRACES OF BETA-AGONISTS AND BETA-ANTAGONISTS | UNIVERSITEIT GENT, LABORATORIUM ORGANISCHE CHEMIE, FAKULTEIT LANDBOUWKUNDIGE EN TOEGEPASTE BIOLOGISCHE WETENSCHAPPEN (BE) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995026330-A1 | ANALYSIS METHOD FOR TESTING FOR TRACES OF BETA-AGONISTS AND BETA-ANTAGONISTS | UNIVERSITEIT GENT, LABORATORIUM ORGANISCHE CHEMIE, FAKULTEIT LANDBOUWKUNDIGE EN TOEGEPASTE BIOLOGISCHE WETENSCHAPPEN (BE) | 1995-10-05 | — | — | WO | disclosed |