Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.47 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617308 | 1.00 | KIF11 (0.73) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL12199501 | 0.94 | KIF11 (0.65) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL2490800 | 0.93 | KIF11 (0.60) | KIF11KCNH2SMN1; SMN2SLC6A11 | |
| SCHEMBL24172659 | 0.91 | KIF11 (0.60) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL7090463 | 0.91 | KIF11 (0.60) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL20827845 | 0.90 | KIF11 (0.63) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL16353449 | 0.89 | KIF11 (0.61) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL16209506 | 0.88 | KIF11 (0.60) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL2344128 | 0.88 | KIF11 (0.60) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL2350762 | 0.88 | KIF11 (0.60) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10568822-B2 | Melanogenesis inhibitor comprising d-pantothenyl alcohol, and skin-whitening cosmetic containing same melanogenesis inhibitor | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2020-02-25 | — | — | US | disclosed |
| EP-2380567-B1 | MELANIN PRODUCTION INHIBITOR | POLA CHEM IND INC (JP) | 2019-01-16 | — | — | EP | disclosed |
| EP-2380567-B1 | MELANIN PRODUCTION INHIBITOR | POLA CHEM IND INC (JP) | 2019-01-16 | — | — | EP | disclosed |
| US-20170119638-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2017-05-04 | — | — | US | disclosed |
| EP-3009123-A1 | MELANIN PRODUCTION INHIBITOR | Pola Chemical Industries Inc. (JP) | 2016-04-20 | — | — | EP | disclosed |
| EP-3009123-A1 | MELANIN PRODUCTION INHIBITOR | Pola Chemical Industries Inc. (JP) | 2016-04-20 | — | — | EP | disclosed |
| US-20150328107-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2015-11-19 | — | — | US | disclosed |
| US-20150328107-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2015-11-19 | — | — | US | disclosed |
| EP-2845587-A2 | Melanin production inhibitor | Pola Chemical Industries Inc. (JP) | 2015-03-11 | — | — | EP | disclosed |
| EP-2845587-A2 | Melanin production inhibitor | Pola Chemical Industries Inc. (JP) | 2015-03-11 | — | — | EP | disclosed |
| US-20140363389-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-12-11 | — | — | US | disclosed |
| US-8846012-B2 | Melanin production inhibitor | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-09-30 | — | — | US | disclosed |
| US-8846012-B2 | Melanin production inhibitor | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-09-30 | — | — | US | disclosed |
| EP-2380567-A1 | MELANIN PRODUCTION INHIBITOR | Pola Chemical Industries Inc. (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2011-10-06 | — | — | US | disclosed |
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2011-10-06 | — | — | US | disclosed |
| EP-0739898-B1 | Phosphonomonoester nucleic acids, methods for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2001-09-26 | — | — | EP | disclosed |
| US-6127346-A | FOR THE TREATMENT OF VIRUSES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | disclosed |
| US-5874553-A | ANTIBODIES; INHIBITOR OF GENE EXPRESSION | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |
| EP-0739898-A2 | Phosphonomonoester nucleic acids, methods for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119638-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | MC1R, TYR, NAMPT | KIF11 3669/4885KCNH2 4322/4885SMN1; SMN2 4699/4885 |
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | TYR, F12, TH | KIF11 4556/4885KCNH2 2662/4885SMN1; SMN2 3632/4885 |
| US-10568822-B2 | Melanogenesis inhibitor comprising d-pantothenyl alcohol, and skin-whitening cosmetic containing same melanogenesis inhibitor | MC1R, TYR, NAMPT | KIF11 3669/4885KCNH2 4322/4885SMN1; SMN2 4699/4885 |
| US-20150328107-A1 | MELANIN PRODUCTION INHIBITOR | TYR, MC1R, F12 | KIF11 4605/4885KCNH2 2817/4885SMN1; SMN2 3663/4885 |
| US-20140363389-A1 | MELANIN PRODUCTION INHIBITOR | TYR, F12, MC1R | KIF11 4611/4885KCNH2 2900/4885SMN1; SMN2 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.