SCHEMBL2344128

SCHEMBL2344128

COc1ccc(C(OCCCCCN)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 8/20 0.60
▸ KCNH2 Q12809 1/20 0.60
▸ SLC6A1 P30531 2/20 0.44
▸ SLC6A11 P48066 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ TK2 O00142 4/20 0.41
▸ TDP1 Q9NUW8 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2350762 1.00 KIF11 (0.60) KIF11KCNH2SLC6A1SLC6A11SMN1; SMN2
SCHEMBL16209506 1.00 KIF11 (0.60) KIF11KCNH2SLC6A1SLC6A11SMN1; SMN2
SCHEMBL16353449 0.98 KIF11 (0.61) KIF11KCNH2SLC6A1SLC6A11SMN1; SMN2
SCHEMBL20827845 0.94 KIF11 (0.63) KIF11KCNH2SLC6A1SLC6A11SMN1; SMN2
SCHEMBL2490823 0.88 KIF11 (0.73) KIF11KCNH2SLC6A1SLC6A11SMN1; SMN2
SCHEMBL3617308 0.88 KIF11 (0.73) KIF11KCNH2SLC6A1SLC6A11SMN1; SMN2
SCHEMBL2493851 0.88 KIF11 (0.53) KIF11KCNH2SLC6A11
SCHEMBL8703547 0.87 KIF11 (0.71) KIF11KCNH2TK2
SCHEMBL5819858 0.87 KIF11 (0.47) KIF11KCNH2SLC6A1SLC6A11TK2
SCHEMBL18413416 0.87 KIF11 (0.47) KIF11KCNH2SLC6A1SLC6A11TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260009026-A1 Capped RNA and Method for Producing Same, Apparatus for Producing Protein, and Method for Producing Protein JAPAN SCIENCE & TECH AGENCY (JP) 2026-01-08 — — US disclosed
EP-4509608-A1 CAPPED RNA AND METHOD FOR PRODUCING SAME, APPARATUS FOR PRODUCING PROTEIN, AND METHOD FOR PRODUCING PROTEIN Japan Science and Technology Agency (JP) 2025-02-19 — — EP disclosed
EP-1781675-B1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES INC (US) 2014-03-26 — — EP disclosed
US-8389745-B2 Phosphonate fluorescent dyes and conjugates ELITECH HOLDING B.V. (NL) 2013-03-05 — — US disclosed
US-20120116079-A1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES ELITECHGROUP MDX LLC 2012-05-10 — — US disclosed
US-8008522-B2 Phosphonate fluorescent dyes and conjugates ELITECH HOLDING B.V. (NL) 2011-08-30 — — US disclosed
US-20100261903-A1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES ELITECHGROUP MDX LLC 2010-10-14 — — US disclosed
US-7767834-B2 Phosphonylated fluorescent dyes and conjugates ELITECH HOLDING B.V. (NL) 2010-08-03 — — US disclosed
US-7671218-B2 Phosphonate fluorescent dyes and conjugates Elitech Holdings B.V. (NL) 2010-03-02 — — US disclosed
US-20080207887-A1 PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES, INC. (US) 2008-08-28 — — US disclosed
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates EPOCH BIOSCIENCES, INC. (US) 2007-07-26 — — US disclosed
EP-1781675-A2 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES Epoch Biosciences, Inc. (US) 2007-05-09 — — EP disclosed
US-20060199955-A1 Phosphonylated fluorescent dyes and conjugates EPOCH BIOSCIENCES, INC. (US) 2006-09-07 — — US disclosed
WO-2006020947-A2 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES, INC. (US) 2006-02-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261903-A1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES PHOSPHO1, PFAS, PHPT1 KIF11 1337/4885KCNH2 4693/4885SLC6A1 2016/4885
US-20080207887-A1 PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES PHOSPHO1, PFAS, PHPT1 KIF11 1281/4885KCNH2 4519/4885SLC6A1 3320/4885
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates PHOSPHO1, PFAS, PHPT1 KIF11 1337/4885KCNH2 4693/4885SLC6A1 2016/4885
US-20260009026-A1 Capped RNA and Method for Producing Same, Apparatus for Producing Protein, and Method for Producing Protein RNGTT, RNMT, NSUN3 KIF11 1602/4885KCNH2 4106/4885SLC6A1 4216/4885
US-20060199955-A1 Phosphonylated fluorescent dyes and conjugates PHOSPHO1, PFAS, PHPT1 KIF11 1281/4885KCNH2 4519/4885SLC6A1 3320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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