Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.44 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.44 |
| ▸ | TK2 | O00142 | 2/20 | 0.41 |
| ▸ | DUT | P33316 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24172659 | 1.00 | KIF11 (0.60) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL3617308 | 0.91 | KIF11 (0.73) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL2490823 | 0.91 | KIF11 (0.73) | KIF11KCNH2SMN1; SMN2SLC6A1SLC6A11 | |
| SCHEMBL13671082 | 0.87 | KIF11 (0.78) | KIF11SMN1; SMN2TK2DUT | |
| SCHEMBL4454297 | 0.87 | KIF11 (0.78) | KIF11SMN1; SMN2TK2DUT | |
| SCHEMBL11913616 | 0.87 | KIF11 (0.78) | KIF11SMN1; SMN2TK2DUT | |
| SCHEMBL28661706 | 0.87 | KIF11 (0.78) | KIF11SMN1; SMN2TK2DUT | |
| SCHEMBL2385290 | 0.85 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11TK2 | |
| SCHEMBL21574354 | 0.85 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11TK2 | |
| SCHEMBL6040158 | 0.85 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833940-B1 | ENCODED REACTION CASSETTE | SCRIPPS RESEARCH INST (US) | 2003-08-06 | — | — | EP | disclosed |