SCHEMBL24908673

SCHEMBL24908673

CCCNC(=O)C(c1cccs1)N1C(=O)c2cc(Oc3cccc(C(C)C)c3)c3c4c(Oc5cccc(C(C)C)c5)cc5c6c(cc(Oc7cccc(C(C)C)c7)c(c7c(Oc8cccc(C(C)C)c8)cc(c2c37)C1=O)c64)C(=O)N(C(C(=O)NCCC)c1cccs1)C5=O

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PTGER3 P43115 1/20 0.33
GLI1 P08151 1/20 0.33
GLI2 P10070 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
CASP1 P29466 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SLC6A2 P23975 5/20 0.31
CACNA2D1 P54289 5/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24705656 0.77 GAA (0.31) GAANPSR1
SCHEMBL24740736 0.75
SCHEMBL24909107 0.73 SMN1; SMN2 (0.40) MEN1KMT2ACASP1SMN1; SMN2ALDH1A1
SCHEMBL24908672 0.73 ALDH1A1 (0.32) ALDH1A1
SCHEMBL24908755 0.72 KDM4E (0.37) BCHEACHECASP1SMN1; SMN2ALDH1A1
SCHEMBL24705311 0.72 BRAF (0.33) GLI1GLI2CASP1SMN1; SMN2L3MBTL1
SCHEMBL24909346 0.72 MAPT (0.41) GAANPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL24908975 0.72 L3MBTL1 (0.41) L3MBTL1
SCHEMBL24908683 0.70 THRB (0.37) CASP1SMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL24908678 0.68 SMN1; SMN2 (0.44) KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed