Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21201454 | 0.82 | IDO1 (0.37) | MAPK1TDP1IDO1 | |
| SCHEMBL3336251 | 0.77 | VCAM1 (0.48) | MAPK1IDO1VCAM1 | |
| SCHEMBL95478 | 0.76 | TP53 (0.48) | MAPK1TDP1VCAM1 | |
| SCHEMBL6212276 | 0.73 | PTGDR2 (0.36) | MAPK1TDP1VCAM1 | |
| SCHEMBL6897410 | 0.73 | ALDH1A1 (0.40) | MAPK1TDP1VCAM1 | |
| SCHEMBL95554 | 0.71 | ERN1 (0.31) | — | |
| SCHEMBL80565 | 0.69 | — | — | |
| SCHEMBL30469268 | 0.69 | — | — | |
| SCHEMBL2515789 | 0.68 | PTGDR2 (0.43) | — | |
| SCHEMBL5969859 | 0.68 | ACACB (0.42) | MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111410639-B | Preparation method of empagliflozin intermediate impurity | 天津法莫西医药科技有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-111410639-A | Preparation method of empagliflozin intermediate impurity | 天津法莫西医药科技有限公司 | 2020-07-14 | — | — | CN | disclosed |
| EP-2183263-B1 | METHODS AND COMPOUNDS USEFUL FOR THE PREPARATION OF SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS | LEXICON PHARMACEUTICALS INC (US) | 2011-10-26 | — | — | EP | disclosed |
| CN-1161336-C | Quinoline carboxamides as antiviral agents | �������Ŷ���Լ��������˾ | 2004-08-11 | — | — | CN | disclosed |
| CN-1333753-A | Quinoline carboxamides as antiviral agents | UPJOHN CO (US) | 2002-01-30 | — | — | CN | disclosed |