SCHEMBL24908946

SCHEMBL24908946

CCC(C)C(C(=O)Nc1ccc2ccccc2c1)N1C(=O)c2cc(Oc3ccc(C(C)(C)C)cc3)c3c4c(Oc5ccc(C(C)(C)C)cc5)cc5c6c(cc(Oc7ccc(C(C)(C)C)cc7)c(c7c(Oc8ccc(C(C)(C)C)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(C(=O)Nc1ccc2ccccc2c1)C(C)CC)C5=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
ATM Q13315 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.37
PKM P14618 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
TP53 P04637 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TSHR P16473 1/20 0.36
ENPP1 P22413 1/20 0.35
RAB9A P51151 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPC1 O15118 2/20 0.34
DNMT1 P26358 3/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909321 0.84 MAPT (0.40) GAASMN1; SMN2LMNAMAPTALDH1A1
SCHEMBL24908667 0.83 TP53 (0.48) GAASMN1; SMN2LMNAMAPTALDH1A1
SCHEMBL24908697 0.80 KDM4E (0.44) GAASMN1; SMN2MAPTALDH1A1TP53
SCHEMBL24908751 0.78 MAPK14 (0.45) SMN1; SMN2LMNAMAPTALDH1A1TP53
SCHEMBL24909067 0.78 TP53 (0.41) GAAATMSMN1; SMN2LMNAMAPT
SCHEMBL24909227 0.78 TP53 (0.44) GAASMN1; SMN2LMNAMAPTALDH1A1
SCHEMBL24908987 0.77 MAPT (0.55) MAPTALDH1A1TP53NPSR1L3MBTL1
SCHEMBL24909234 0.76 ALDH1A1 (0.42) ATMSMN1; SMN2LMNAMAPTALDH1A1
SCHEMBL24908968 0.75 RAF1 (0.39) SMN1; SMN2LMNAMAPTALDH1A1MAPK1
SCHEMBL24908715 0.74 DNMT1 (0.39) SMN1; SMN2ALDH1A1TP53NPSR1DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed