SCHEMBL24908751

SCHEMBL24908751

CC(C)C(C(=O)Nc1cccc2ccccc12)N1C(=O)c2cc(Oc3ccc(C(C)(C)C)cc3)c3c4c(Oc5ccc(C(C)(C)C)cc5)cc5c6c(cc(Oc7ccc(C(C)(C)C)cc7)c(c7c(Oc8ccc(C(C)(C)C)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(C(=O)Nc1cccc2ccccc12)C(C)C)C5=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 4/20 0.45
NLRP3 Q96P20 1/20 0.41
TP53 P04637 1/20 0.39
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 2/20 0.39
MAPT P10636 1/20 0.38
RECQL P46063 1/20 0.38
PLAU P00749 1/20 0.37
ELANE P08246 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
TRPV1 Q8NER1 1/20 0.36
P2RY1 P47900 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24908667 0.85 TP53 (0.48) MAPK14TP53KMT2AMEN1KDM4E
SCHEMBL24739688 0.83 MAPT (0.41) TP53KMT2AMEN1KDM4EALDH1A1
SCHEMBL24909227 0.81 TP53 (0.44) MAPK14TP53KMT2AKDM4EALDH1A1
SCHEMBL24909308 0.80 L3MBTL1 (0.39) TP53KMT2AMEN1ALDH1A1MAPT
SCHEMBL24909038 0.80 MAPT (0.34) KMT2AMEN1ALDH1A1HPGDMAPT
SCHEMBL24908715 0.80 DNMT1 (0.39) TP53ALDH1A1HPGDSMN1; SMN2NPSR1
SCHEMBL24908682 0.79 TP53 (0.34) MAPK14TP53KMT2AALDH1A1HPGD
SCHEMBL24908946 0.78 GAA (0.41) TP53KMT2AMEN1ALDH1A1MAPT
SCHEMBL24908957 0.78 ALDH1A1 (0.41) TP53KMT2AMEN1KDM4EALDH1A1
SCHEMBL24908754 0.77 NPSR1 (0.37) TP53KMT2AMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed