SCHEMBL24909321

SCHEMBL24909321

CC(C)(C)c1ccc(Oc2cc3c4c(cc(Oc5ccc(C(C)(C)C)cc5)c5c6c(Oc7ccc(C(C)(C)C)cc7)cc7c8c(cc(Oc9ccc(C(C)(C)C)cc9)c(c2c45)c86)C(=O)N(C(CC(F)(F)F)C(=O)Nc2ccc4ccccc4c2)C7=O)C(=O)N(C(CC(F)(F)F)C(=O)Nc2ccc4ccccc4c2)C3=O)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
NPSR1 Q6W5P4 1/20 0.40
DNMT1 P26358 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 2/20 0.38
TP53 P04637 1/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
ENPP1 P22413 1/20 0.35
USP2 O75604 1/20 0.35
TSHR P16473 1/20 0.35
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
BRAF P15056 1/20 0.34
ABL1 P00519 1/20 0.33
GAA P10253 1/20 0.33
PARG Q86W56 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24704952 0.86 L3MBTL1 (0.35) MAPTNPSR1DNMT1SMN1; SMN2LMNA
SCHEMBL24705442 0.84 L3MBTL1 (0.35) MAPTNPSR1DNMT1SMN1; SMN2LMNA
SCHEMBL24908946 0.84 GAA (0.41) MAPTNPSR1DNMT1SMN1; SMN2LMNA
SCHEMBL24909005 0.82 DNMT1 (0.35) NPSR1DNMT1SMN1; SMN2TP53ALDH1A1
SCHEMBL24908987 0.82 MAPT (0.55) MAPTNPSR1DNMT1TP53MEN1
SCHEMBL24908697 0.80 KDM4E (0.44) MAPTSMN1; SMN2TP53MEN1KMT2A
SCHEMBL24908737 0.79 ALDH1A1 (0.35) MAPTNPSR1SMN1; SMN2LMNATP53
SCHEMBL24909137 0.78 MAPT (0.41) MAPTNPSR1SMN1; SMN2LMNATP53
SCHEMBL24908968 0.77 RAF1 (0.39) MAPTNPSR1DNMT1SMN1; SMN2LMNA
SCHEMBL24908667 0.76 TP53 (0.48) MAPTNPSR1SMN1; SMN2LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed
US-9624160-B2 Reactive ionic liquids BASF SE (DE) 2017-04-18 US disclosed