SCHEMBL24909289

SCHEMBL24909289

CCOC(=O)CN1C(=O)c2cc(Oc3ccc(C)cc3)c3c4c(Oc5ccc(C)cc5)cc5c6c(cc(Oc7ccc(C)cc7)c(c7c(Oc8ccc(C)cc8)cc(c2c37)C1=O)c64)C(=O)N(CC(=O)OCC)C5=O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.61
PIN4 Q9Y237 1/20 0.61
LPAR1 Q92633 1/20 0.51
LPAR3 Q9UBY5 1/20 0.51
ALDH1A1 P00352 4/20 0.50
MAPT P10636 1/20 0.45
HTT P42858 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PPARG P37231 1/20 0.45
KMT2A Q03164 4/20 0.44
MEN1 O00255 2/20 0.44
RAB9A P51151 1/20 0.44
RXFP1 Q9HBX9 1/20 0.43
LMNA P02545 1/20 0.43
CYP2C19 P33261 1/20 0.43
GSK3A P49840 1/20 0.43
GSK3B P49841 1/20 0.43
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909290 0.86 LPAR3 (0.68) PIN1PIN4LPAR1LPAR3ALDH1A1
SCHEMBL24705776 0.85 LPAR1 (0.44) PIN1PIN4LPAR1LPAR3ALDH1A1
SCHEMBL24705221 0.84 LPAR1 (0.43) PIN1PIN4LPAR1LPAR3ALDH1A1
SCHEMBL24705758 0.83 ALDH1A1 (0.44) PIN1PIN4LPAR1LPAR3ALDH1A1
SCHEMBL24908997 0.79 LPAR1 (0.43) PIN1PIN4LPAR1LPAR3ALDH1A1
SCHEMBL16786454 0.78 ALDH1A1 (0.44) LPAR1LPAR3ALDH1A1MAPTHTT
SCHEMBL24705409 0.78 LPAR1 (0.43) PIN1PIN4LPAR1LPAR3ALDH1A1
SCHEMBL442751 0.77 PIN1 (1.00) PIN1PIN4ALDH1A1MAPTHTT
SCHEMBL24705393 0.77 LPAR1 (0.45) LPAR1LPAR3ALDH1A1KMT2ARAB9A
SCHEMBL24705381 0.77 LPAR1 (0.42) LPAR1LPAR3ALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed