SCHEMBL24908997

SCHEMBL24908997

CCN(C(=O)CN1C(=O)c2cc(Oc3ccc(C)cc3)c3c4c(Oc5ccc(C)cc5)cc5c6c(cc(Oc7ccc(C)cc7)c(c7c(Oc8ccc(C)cc8)cc(c2c37)C1=O)c64)C(=O)N(CC(=O)N(CC)c1ccncc1)C5=O)c1ccncc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 1/20 0.43
LPAR3 Q9UBY5 1/20 0.43
PIN1 Q13526 1/20 0.37
PIN4 Q9Y237 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.37
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
KMT2A Q03164 3/20 0.35
MMP13 P45452 2/20 0.35
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
TDP1 Q9NUW8 2/20 0.34
MEN1 O00255 2/20 0.34
GAA P10253 1/20 0.34
RAD52 P43351 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
GALR3 O60755 1/20 0.33
MMP2 P08253 1/20 0.33
CYP3A4 P08684 1/20 0.33
STAT3 P40763 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909289 0.79 PIN1 (0.61) LPAR1LPAR3PIN1PIN4LMNA
SCHEMBL24909290 0.78 LPAR3 (0.68) LPAR1LPAR3PIN1PIN4KMT2A
SCHEMBL24705153 0.77 LPAR1 (0.40) LPAR1LPAR3PIN1PIN4KMT2A
SCHEMBL24705409 0.76 LPAR1 (0.43) LPAR1LPAR3PIN1PIN4KMT2A
SCHEMBL24908966 0.76 TRPM8 (0.31) TRPM8
SCHEMBL24739827 0.71 ALDH1A1 (0.46) LPAR1LPAR3PIN1PIN4LMNA
SCHEMBL24705393 0.71 LPAR1 (0.45) LPAR1LPAR3LMNAKMT2AALDH1A1
SCHEMBL24909256 0.71 ALDH1A1 (0.43) LPAR1LPAR3LMNAKMT2AMMP13
SCHEMBL24705091 0.71 LPAR1 (0.37) LPAR1LPAR3LMNAKMT2AMMP13
SCHEMBL16786454 0.70 ALDH1A1 (0.44) LPAR1LPAR3LMNAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed