SCHEMBL24909355

SCHEMBL24909355

C=Cc1cccc(-c2cc(C#N)cc(Br)c2O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.47
ALB P02768 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
PTGS2 P35354 1/20 0.34
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
P4HB P07237 3/20 0.33
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
FBP1 P09467 2/20 0.32
SIRT1 Q96EB6 1/20 0.32
XDH P47989 3/20 0.31
SLC22A12 Q96S37 3/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909393 0.85 TTR (0.51) TTRALBMEN1KMT2AMAOA
SCHEMBL24909749 0.83 MEN1 (0.56) TTRALBMEN1KMT2AMAOB
SCHEMBL24910032 0.81 MEN1 (0.55) TTRALBMEN1KMT2AMAOA
SCHEMBL29936349 0.80 MEN1 (0.53) TTRALBMEN1KMT2ACRHBP
SCHEMBL23621220 0.80 MEN1 (0.53) TTRALBMEN1KMT2ACRHBP
SCHEMBL24909360 0.79 MEN1 (0.60) TTRALBMEN1KMT2AMAOA
SCHEMBL24909685 0.79 TTR (0.51) TTRALBMEN1KMT2AKDM4E
SCHEMBL24909835 0.79 MEN1 (0.51) TTRALBMEN1KMT2ATDP1
SCHEMBL24909705 0.76 TTR (0.47) TTRALBMEN1KMT2ATP53
SCHEMBL24909868 0.76 MEN1 (0.47) TTRALBMEN1KMT2AXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 TTR 4497/4885ALB 3928/4885MEN1 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.