SCHEMBL24909690

SCHEMBL24909690

CC(C)(S)C(=O)OCC(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.52
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
FABP7 O15540 1/20 0.31
PRKCA P17252 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19857462 0.81 HTT (0.50) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL1171107 0.81 MAPK1 (0.34) HTTALDH1A1HSD17B10PRKCA
SCHEMBL2692345 0.81 HTT (0.50) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL23005578 0.81 HTT (0.50) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL3095013 0.81 LMNA (0.39) HTTALDH1A1TSHRHSD17B10PRKCA
SCHEMBL13610613 0.81 POLB (0.40) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL22915535 0.78 HTT (0.48) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL5362241 0.77 HTT (0.46) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL5355110 0.77 HTT (0.46) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL28024337 0.77 HTT (0.46) HTTMEN1ALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230025932-A1 NOVEL FUNCTIONALIZED LACTONES AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE PRAEVENTIX, LLC 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230025932-A1 NOVEL FUNCTIONALIZED LACTONES AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE HTR7, HTR2C, HTR3A HTT 1551/4885MEN1 3075/4885ALDH1A1 2783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.