SCHEMBL24909741

SCHEMBL24909741

COCc1cccc(-c2cc(C#N)cc(Br)c2O)c1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
TTR P02766 1/20 0.44
ALB P02768 1/20 0.44
KMT2A Q03164 1/20 0.44
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42
ERN1 O75460 1/20 0.41
MMP3 P08254 2/20 0.36
DYRK1A Q13627 1/20 0.36
GRM5 P41594 2/20 0.35
BRD4 O60885 1/20 0.35
CREBBP Q92793 1/20 0.35
FFAR1 O14842 4/20 0.35
MRGPRX4 Q96LA9 2/20 0.33
HTR7 P34969 1/20 0.33
ALOX5 P09917 1/20 0.33
MMP2 P08253 1/20 0.33
USP7 Q93009 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909906 0.86 TTR (0.47) MEN1TTRALBKMT2AERN1
SCHEMBL24909378 0.82 MRGPRX4 (0.43) FNTAFNTBERN1DYRK1AGRM5
SCHEMBL24909749 0.80 MEN1 (0.56) MEN1TTRALBKMT2AUSP7
SCHEMBL24909685 0.79 TTR (0.51) MEN1TTRALBKMT2A
SCHEMBL24910032 0.78 MEN1 (0.55) MEN1TTRALBKMT2A
SCHEMBL23621220 0.77 MEN1 (0.53) MEN1TTRALBKMT2AGRM5
SCHEMBL29936349 0.77 MEN1 (0.53) MEN1TTRALBKMT2AGRM5
SCHEMBL24909360 0.76 MEN1 (0.60) MEN1TTRALBKMT2A
SCHEMBL24909835 0.76 MEN1 (0.51) MEN1TTRALBKMT2AFNTA
SCHEMBL24909705 0.75 TTR (0.47) MEN1TTRALBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 MEN1 3221/4885TTR 4497/4885ALB 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.