SCHEMBL24909747

SCHEMBL24909747

N#Cc1cc(Br)c(O)c(-c2ccc3c(c2)OCO3)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
TTR P02766 1/20 0.47
ALB P02768 1/20 0.47
XDH P47989 1/20 0.46
SLC22A12 Q96S37 1/20 0.46
MAPT P10636 4/20 0.46
ALOX15 P16050 2/20 0.46
HSD17B10 Q99714 2/20 0.46
HTT P42858 1/20 0.46
BCL2L1 Q07817 1/20 0.44
ADORA1 P30542 1/20 0.42
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 1/20 0.41
HPGD P15428 1/20 0.41
ALOX12 P18054 1/20 0.41
NPC1 O15118 1/20 0.40
GAA P10253 1/20 0.40
GSK3A P49840 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909809 0.79 MEN1 (0.45) MEN1KMT2ATTRALBXDH
SCHEMBL5098907 0.79 BCL2L1 (0.52) MEN1KMT2AXDHSLC22A12MAPT
SCHEMBL24909826 0.78 TTR (0.62) MEN1KMT2ATTRALBXDH
SCHEMBL24909772 0.74 TTR (0.53) MEN1KMT2ATTRALBXDH
SCHEMBL24910063 0.74 TTR (0.53) MEN1KMT2ATTRALBXDH
SCHEMBL5098807 0.74 FNTA (0.51) MEN1KMT2AMAPTALOX15HSD17B10
SCHEMBL24909749 0.74 MEN1 (0.56) MEN1KMT2ATTRALBXDH
SCHEMBL24909714 0.74 TTR (0.56) MEN1KMT2ATTRALBXDH
SCHEMBL5091184 0.73 MAPT (0.49) MEN1KMT2AMAPTALOX15HSD17B10
SCHEMBL24909360 0.73 MEN1 (0.60) MEN1KMT2ATTRALBXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 MEN1 3221/4885KMT2A 847/4885TTR 4497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.