SCHEMBL24909809

SCHEMBL24909809

N#Cc1cc(Br)c(O)c(-c2ccc3c(c2)OC(F)(F)O3)c1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
TTR P02766 1/20 0.45
ALB P02768 1/20 0.45
KMT2A Q03164 1/20 0.45
FNTA P49354 2/20 0.39
FNTB P49356 2/20 0.39
NOTUM Q6P988 1/20 0.35
KIF11 P52732 1/20 0.35
SCN9A Q15858 1/20 0.35
XDH P47989 10/20 0.34
SLC22A12 Q96S37 10/20 0.34
PGGT1B P53609 2/20 0.34
TDP2 O95551 2/20 0.33
CYP2C8 P10632 1/20 0.32
CYP2C9 P11712 1/20 0.32
KIT P10721 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909402 0.82 XDH (0.40) FNTAFNTBNOTUMKIF11SCN9A
SCHEMBL24909828 0.81 MEN1 (0.41) MEN1TTRALBKMT2AFNTA
SCHEMBL5099677 0.80 KDM1A (0.45) FNTAFNTBNOTUMKIF11SCN9A
SCHEMBL24909747 0.79 MEN1 (0.47) MEN1TTRALBKMT2AFNTA
SCHEMBL24909826 0.76 TTR (0.62) MEN1TTRALBKMT2AKIF11
SCHEMBL24909772 0.75 TTR (0.53) MEN1TTRALBKMT2AFNTA
SCHEMBL24909714 0.75 TTR (0.56) MEN1TTRALBKMT2AXDH
SCHEMBL24909769 0.73 TTR (0.50) MEN1TTRALBKMT2AXDH
SCHEMBL23621220 0.72 MEN1 (0.53) MEN1TTRALBKMT2A
SCHEMBL24910063 0.72 TTR (0.53) MEN1TTRALBKMT2AXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 MEN1 3221/4885TTR 4497/4885ALB 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.