SCHEMBL24909869

SCHEMBL24909869

O=P(O)(S)OCCOP(=O)(O)S

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 4/20 0.33
LPAR2 Q9HBW0 3/20 0.33
LPAR1 Q92633 2/20 0.33
KDM4E B2RXH2 1/20 0.32
MMP2 P08253 1/20 0.32
THRB P10828 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
FDPS P14324 1/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909981 0.88 LPAR3 (0.41) LPAR3LPAR2LPAR1
SCHEMBL7146590 0.85
SCHEMBL1973590 0.83
SCHEMBL8147108 0.83
SCHEMBL5585476 0.81
SCHEMBL3512129 0.80 FDPS (0.32) KDM4EMMP2THRBMAPK1HSD17B10
SCHEMBL14320175 0.79 LPAR3 (0.40) LPAR3LPAR2LPAR1ALDH1A1
SCHEMBL21890157 0.79 GABRR1 (0.32) FDPS
SCHEMBL483082 0.79
SCHEMBL25422682 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230017490-A1 STING INHIBITORS AND THEIR THERAPEUTIC USES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230017490-A1 STING INHIBITORS AND THEIR THERAPEUTIC USES STING1, CGAS, MAVS LPAR3 1064/4885LPAR2 906/4885LPAR1 743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.