SCHEMBL3512129

SCHEMBL3512129

O=P(O)(S)OCOP(=O)(O)S

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MMP2 P08253 1/20 0.32
THRB P10828 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909869 0.80 LPAR3 (0.33) FDPSKDM4EMMP2THRBMAPK1
SCHEMBL7559551 0.78 CA2 (0.42) FDPSKDM4EMMP2THRBMAPK1
SCHEMBL24909873 0.75 CYP2C9 (0.34)
SCHEMBL24909981 0.75 LPAR3 (0.41)
SCHEMBL11420570 0.75
SCHEMBL7146590 0.73
SCHEMBL25522 0.73
SCHEMBL533763 0.72 FDPS (0.44) FDPSKDM4EMMP2THRBMAPK1
SCHEMBL22636014 0.72 TSHR (0.30)
SCHEMBL8147108 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130101506-A1 COMPOSITIONS COMPRISING NUCLEIC ACID APTAMERS SMITH CASSANDRA L (US) 2013-04-25 US claimed
US-20100254901-A1 Compositions comprising nucleic acid aptamers SMITH CASSANDRA L 2010-10-07 US claimed
CN-119614577-A Anti-CD 3 nucleic acid aptamer for cell targeting and labeling 艾夏卡法国有限公司 2025-03-14 CN disclosed
US-20220251562-A1 Anti-CD3 Aptamers for Use in Cell Targeting and Labeling IXAKA FRANCE (FR) 2022-08-11 US disclosed
EP-4004209-A2 ANTI-CD3 APTAMERS FOR USE IN CELL TARGETING AND LABELING IXAKA FRANCE (FR) 2022-06-01 EP disclosed
WO-2021019301-A2 ANTI-CD3 APTAMERS FOR USE IN CELL TARGETING AND LABELING ARATINGA.BIO ACI (FR) 2021-02-04 WO disclosed
US-20130101506-A1 COMPOSITIONS COMPRISING NUCLEIC ACID APTAMERS SMITH CASSANDRA L (US) 2013-04-25 US disclosed
US-20100254901-A1 Compositions comprising nucleic acid aptamers SMITH CASSANDRA L 2010-10-07 US disclosed