Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24781628 | 0.86 | AKR1C3 (0.57) | AKR1C3AKR1C2PDK2LMNAPTGS1 | |
| SCHEMBL24910319 | 0.85 | AKR1C3 (0.47) | AKR1C3AKR1C2PTPN5CASRLMNA | |
| SCHEMBL24910320 | 0.84 | AKR1C3 (0.51) | AKR1C3AKR1C2PTPN5PDK2LMNA | |
| SCHEMBL24910185 | 0.80 | AKR1C3 (0.51) | AKR1C3AKR1C2PTPN5PDK2LMNA | |
| SCHEMBL12570858 | 0.79 | CNR2 (0.48) | AKR1C3AKR1C2PTPN5LMNAMEN1 | |
| SCHEMBL15340840 | 0.78 | PTPN5 (0.49) | AKR1C3AKR1C2PTPN5HSD11B1 | |
| SCHEMBL10878363 | 0.77 | LMNA (0.54) | AKR1C3AKR1C2PTPN5PDK2METAP2 | |
| SCHEMBL24910239 | 0.77 | AKR1C3 (0.55) | AKR1C3AKR1C2PDK2LMNAAKR1C4 | |
| SCHEMBL24910094 | 0.77 | LMNA (0.41) | AKR1C3AKR1C2PTPN5PDK2CASR | |
| SCHEMBL23149011 | 0.77 | HSD11B1 (0.46) | AKR1C3AKR1C2PDK2HSD11B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122934-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2023-01-25 | — | — | EP | disclosed |