SCHEMBL24910092

SCHEMBL24910092

CC(C)c1cc(-c2c(C(F)(F)F)cccc2C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 4/20 0.41
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
ATM Q13315 1/20 0.39
CTSA P10619 4/20 0.36
CNR1 P21554 2/20 0.35
CNR2 P34972 2/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
P2RX7 Q99572 1/20 0.35
TACR1 P25103 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
PNMT P11086 1/20 0.34
DAO P14920 1/20 0.34
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24910315 0.83 AR (0.41) PTPN5CTSACNR2TACR1AKR1C3
SCHEMBL24910314 0.80 PTPN5 (0.54) PTPN5ALDH1A1GAAATMHTR2A
SCHEMBL21766566 0.79 RXRA (0.40) PTPN5ALDH1A1GAAATMCTSA
SCHEMBL26375466 0.78 NOTUM (0.41) PTPN5ALDH1A1CNR1CNR2
SCHEMBL24780609 0.78 KIF11 (0.48) PTPN5ALDH1A1TACR1AKR1C3AKR1C2
SCHEMBL21766567 0.78 IKBKB (0.35) PTPN5ALDH1A1GAAATMCTSA
SCHEMBL21766570 0.76 ALOX5AP (0.41) CTSAAKR1C3AKR1C2
SCHEMBL24910183 0.76 PTPN5 (0.47) PTPN5ALDH1A1GAAATMAKR1C3
SCHEMBL24754923 0.76 CES2 (0.37) PTPN5ALDH1A1GAAATMCTSA
SCHEMBL24910321 0.76 PSEN1 (0.50) PTPN5AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122934-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-01-25 EP disclosed