SCHEMBL24910309

SCHEMBL24910309

CC(C)c1cc(OC(F)(F)F)ncn1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 2/20 0.34
ALOX5AP P20292 1/20 0.34
FEN1 P39748 1/20 0.34
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
CRHBP P24387 1/20 0.32
CYP2C19 P33261 1/20 0.32
CRHR2 Q13324 1/20 0.32
EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL799179 0.76 CYP2C19 (0.40) ALOX5APFEN1CYP2C19
SCHEMBL25694843 0.75 ALOX5AP (0.33) ALOX5APFEN1
SCHEMBL25106039 0.75 BRAF (0.36) CYP2C19
SCHEMBL26565585 0.74 EGLN2 (0.32)
SCHEMBL15305335 0.73 ACACB (0.37) ALOX5APFEN1
SCHEMBL786348 0.72 NOS3 (0.36) CYP3A4CYP2D6TSHRCRHBPCYP2C19
SCHEMBL24910287 0.72 APLNR (0.34)
SCHEMBL12340827 0.71 CA2 (0.50) PDE2ACYP3A4CYP2D6TSHRCRHBP
SCHEMBL22489576 0.70 IDH1 (0.39) PDE2ACYP3A4CYP2D6TSHRCRHBP
SCHEMBL10175737 0.70 ALOX5AP (0.32) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122934-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-01-25 EP disclosed