SCHEMBL24910409

SCHEMBL24910409

CC(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1-c1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 1/20 0.38
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
NOTUM Q6P988 1/20 0.32
RXRA P19793 2/20 0.32
RXRB P28702 2/20 0.32
RXRG P48443 1/20 0.32
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
PTPN5 P54829 1/20 0.31
GABRA1 P14867 2/20 0.31
GABRG2 P18507 2/20 0.31
GABRB3 P28472 2/20 0.31
PDE2A O00408 2/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRA5 P31644 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26383676 0.88 PDE2A (0.32) NOTUMRXRARXRBRXRGPDE2A
SCHEMBL26383807 0.87 PDE2A (0.34) PDE2A
SCHEMBL26382557 0.83 NOTUM (0.38) IKBKBNOTUMAKR1C3AKR1C2
SCHEMBL26383805 0.81 KIF11 (0.35) PDE2A
SCHEMBL24910289 0.79 P2RX7 (0.39) PTPN5PDE2A
SCHEMBL24910408 0.78 PDE2A (0.38) PDE2ACES2
SCHEMBL26375504 0.77 IKBKB (0.46) IKBKBCNR1CNR2NOTUMRXRA
SCHEMBL26383811 0.77 PDE2A (0.31) PDE2A
SCHEMBL26383397 0.76 IKBKB (0.36) IKBKBCNR1CNR2RXRARXRB
SCHEMBL26382558 0.76 RXRA (0.38) IKBKBRXRARXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122934-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-01-25 EP disclosed