Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 11/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 11/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 11/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 11/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14820152 | 0.84 | — | — | |
| SCHEMBL12457855 | 0.84 | — | — | |
| SCHEMBL12457674 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL38659177 | 0.82 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL21038312 | 0.77 | CHRNB2 (0.30) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL15338322 | 0.74 | MBTD1 (0.34) | — | |
| SCHEMBL12560847 | 0.74 | MBTD1 (0.34) | — | |
| SCHEMBL18967092 | 0.74 | MBTD1 (0.34) | — | |
| SCHEMBL23866134 | 0.74 | MBTD1 (0.34) | — | |
| SCHEMBL18967101 | 0.74 | MBTD1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601297-B9 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC (US) | 2023-05-24 | — | — | EP | disclosed |