Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | HPGD | P15428 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | HTR1A | P08908 | 2/20 | 0.76 |
| ▸ | HTR2C | P28335 | 1/20 | 0.76 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.64 |
| ▸ | TUBB | P07437 | 2/20 | 0.64 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.64 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.64 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.64 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.64 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.64 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.64 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.64 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.64 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491159 | 1.00 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| Hydrochloric Acid SCHEMBL9043399 | 0.98 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL16692736 | 0.90 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL15884131 | 0.89 | GAA (0.78) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| Sinapic Acid Methyl Ether SCHEMBL207442 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| Sinapic Acid Methyl Ether SCHEMBL207441 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL7997553 | 0.86 | TUBB4A (0.62) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL7997556 | 0.86 | TUBB4A (0.62) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL15884125 | 0.86 | TUBB4A (0.62) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| Sinapic Acid Methyl Ether SCHEMBL9757598 | 0.85 | KDM4E (0.96) | KDM4EALDH1A1HPGDHSD17B10HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103694282-B | A kind of method of synthesizing Tenuifoliside B | ZHEJIANG UNIVERSITY (CN) | 2015-12-09 | — | — | CN | claimed |
| CN-103694282-A | Synthetic method of Tenuifoliside B | UNIV ZHEJIANG | 2014-04-02 | — | — | CN | claimed |
| EP-3592341-B1 | TOPICAL COMPOSITIONS CONTAINING SYNTHETIC ESTERS OF SINAPINIC ACID AND METHODS FOR TREATING KERATIN SURFACES | ELC MAN LLC (US) | 2021-12-01 | — | — | EP | disclosed |
| US-20210137805-A1 | TOPICAL COMPOSITIONS CONTAINING SYNTHETIC ESTERS OF SINAPINIC ACID AND METHODS FOR TREATING KERATIN SURFACES | ELC MANAGEMENT LLC | 2021-05-13 | — | — | US | disclosed |
| EP-2943478-B1 | NOVEL DERIVATIVES OF SINAPINIC ACID | PHARMASYNTHESE (FR) | 2017-08-02 | — | — | EP | disclosed |
| EP-2917263-B1 | POLY(DIHYDROFERULIC ACID) A BIORENEWABLE POLYETHYLENE TEREPHTHALATE MIMIC DERIVED FROM LIGNIN AND ACETIC ACID AND COPOLYMERS THEREOF | UNIV FLORIDA (US) | 2017-06-21 | — | — | EP | disclosed |
| US-9624340-B2 | Poly(dihydroferulic acid) a biorenewable polyethylene terephthalate mimic derived from lignin and acetic acid and copolymers thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-9463338-B2 | Derivatives of the sinapinic acid | PHARMASYNTHESE (FR) | 2016-10-11 | — | — | US | disclosed |
| US-9463338-B2 | Derivatives of the sinapinic acid | PHARMASYNTHESE (FR) | 2016-10-11 | — | — | US | disclosed |
| US-20150353469-A1 | DERIVATIVES OF THE SINAPINIC ACID | PHARMASYNTHESE (FR) | 2015-12-10 | — | — | US | disclosed |
| US-20150353469-A1 | DERIVATIVES OF THE SINAPINIC ACID | PHARMASYNTHESE (FR) | 2015-12-10 | — | — | US | disclosed |
| US-5344845-A | Methyl 4(4-acetoxy-3-methoxycinnamanide and salts as an immunosuppressive drug for allergic reactions | TSUMURA & CO. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0505565-B1 | QUINOLINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-04-27 | — | — | EP | disclosed |
| US-5278186-A | Substituted with secondary amide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-01-11 | — | — | US | disclosed |
| US-5256782-A | For anticholesterol agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0535250-A1 | NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE | TSUMURA & CO. (JP) | 1993-04-07 | — | — | EP | disclosed |
| EP-0505565-A1 | QUINOLINE DERIVATIVES, THEIR PRODUCTION AND USE. | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-09-30 | — | — | EP | disclosed |
| US-5143919-A | Acyl-CoA:cholesterol acyltransferase inhibitors; anticholesterol agents; | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0472116-A1 | Thienopyridine Derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-02-26 | — | — | EP | disclosed |
| WO-1991009017-A1 | QUINOLINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353469-A1 | DERIVATIVES OF THE SINAPINIC ACID | ASAH1, ASAH2, ALDH7A1 | KDM4E 4456/4885ALDH1A1 85/4885HPGD 912/4885 |
| US-20210137805-A1 | TOPICAL COMPOSITIONS CONTAINING SYNTHETIC ESTERS OF SINAPINIC ACID AND METHODS FOR TREATING KERATIN SURFACES | KRT18, CUTA, CKAP4 | KDM4E 1951/4885ALDH1A1 2869/4885HPGD 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.