Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.62 |
| ▸ | TUBB | P07437 | 2/20 | 0.62 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.62 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.62 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.62 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.62 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.62 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.62 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.62 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.62 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.62 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.62 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.62 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.62 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997553 | 1.00 | TUBB4A (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16692730 | 0.90 | TUBB4A (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15884131 | 0.87 | GAA (0.78) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8637989 | 0.87 | ALDH1A1 (0.72) | GAAHTTHTR1AKDM4EALDH1A1 | |
| SCHEMBL8637983 | 0.87 | ALDH1A1 (0.72) | GAAHTTHTR1AKDM4EALDH1A1 | |
| SCHEMBL2491159 | 0.86 | KDM4E (0.76) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2491158 | 0.86 | KDM4E (0.76) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15884125 | 0.84 | TUBB4A (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL9043399 | 0.84 | KDM4E (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL23353439 | 0.83 | TUBB4A (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |
| EP-0472116-B1 | Thienopyridine Derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5256782-A | For anticholesterol agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| US-5143919-A | Acyl-CoA:cholesterol acyltransferase inhibitors; anticholesterol agents; | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0472116-A1 | Thienopyridine Derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-02-26 | — | — | EP | disclosed |