SCHEMBL2491301

SCHEMBL2491301

Nc1nnc(C(=O)O)[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL15332100 0.98 LMNA (0.35)
SCHEMBL12050697 0.75 LMNA (0.37)
SCHEMBL19914387 0.73 MAP4K1 (0.36)
SCHEMBL868038 0.73 TSHR (0.39)
SCHEMBL9921354 0.72
SCHEMBL4858369 0.70
SCHEMBL11588433 0.70
SCHEMBL14770091 0.70
SCHEMBL20023168 0.70
SCHEMBL2941533 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101604607-A Coating composition for interconnection part of electrode and comprise its plasma display SAMSUNG SDI CO LTD (KR) 2009-12-16 CN claimed
EP-2014797-A2 Coating composition for interconnection part of electrode and plasma display panel including the same Samsung SDI Co., Ltd. (KR) 2009-01-14 EP claimed
US-20080303439-A1 Coating composition for interconnection part of electrode and plasma display panel including the same SAMSUNG SDI CO., LTD., A CORP. OF THE REPUBLIC OF KOREA (KR) 2008-12-11 US claimed
US-20230416228-A1 AGENTS FOR THE TREATMENT OF DISEASES BY INHIBITION OF FOXO1 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEWYORK 2023-12-28 US disclosed
EP-4217355-A1 AGENTS FOR THE TREATMENT OF DISEASES BY INHIBITION OF FOXO1 Forkhead Biotherapeutics, inc. (US) 2023-08-02 EP disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
WO-2022066938-A1 AGENTS FOR THE TREATMENT OF DISEASES BY INHIBITION OF FOXO1 FORKHEAD BIOTHERAPEUTICS, INC. (US) 2022-03-31 WO disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
US-11078196-B2 Heteroaryl amides as inhibitors of protein aggregation UCB Biophama SRL (BE) 2021-08-03 US disclosed
EP-3348556-B1 HETEROARYL AMIDES AS INHIBITORS OF PROTEIN AGGREGATION UCB Biopharma SRL (BE) 2020-04-29 EP disclosed
US-20190308965-A1 HETEROARYL AMIDES AS INHIBITORS OF PROTEIN AGGREGATION UCB BIOPHARMA SPRL (BE) 2019-10-10 US disclosed
US-7345043-B2 Inhibitors of histone deacetylase MIIKANA THERAPEUTICS (US) 2008-03-18 US disclosed
US-7345043-B2 Inhibitors of histone deacetylase MIIKANA THERAPEUTICS (US) 2008-03-18 US disclosed
WO-2007045829-A2 YELLOW AZO DYES FOR INK JET PRINTING FUJIFILM IMAGING COLORANTS LIMITED (GB) 2007-04-26 WO disclosed
EP-1755601-A2 INHIBITORS OF HISTONE DEACETYLASE Miikana Therapeutics, Inc. (US) 2007-02-28 EP disclosed
US-20050250784-A1 Inhibitors of histone deacetylase MIIKANA THERAPEUTICS CORPORATION 2005-11-10 US disclosed
US-20050234033-A1 Inhibitors of histone deacetylase MIIKANA THERAPEUTICS 2005-10-20 US disclosed
WO-2005086898-A2 INHIBITORS OF HISTONE DEACETYLASE MIIKANA THERAPEUTICS, INC. (US) 2005-09-22 WO disclosed
US-6712890-B2 WATER SOLUBLE DYES HAVING GOOD LIGHTFASTNESS AND OPTICAL DENSITY AVECIA LIMITED (GB) 2004-03-30 US disclosed
US-20020130937-A1 Compositions AVECIA LIMITED 2002-09-19 US disclosed