⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11588433 | 0.70 | — | — | |
| SCHEMBL2941533 | 0.70 | — | — | |
| SCHEMBL14770091 | 0.70 | — | — | |
| SCHEMBL12050697 | 0.70 | LMNA (0.37) | — | |
| SCHEMBL20023168 | 0.70 | — | — | |
| Water SCHEMBL15332100 | 0.68 | LMNA (0.35) | — | |
| SCHEMBL5481299 | 0.67 | — | — | |
| SCHEMBL12050708 | 0.67 | LMNA (0.34) | — | |
| SCHEMBL2177061 | 0.65 | PIN1 (0.38) | — | |
| SCHEMBL2147297 | 0.65 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057053-B | 5-Membered heteroaryl derivatives containing at least one N and pharmaceutical compositions containing the same as active ingredient for preventing or treating mental disorders | 特立尼奥公司 | 2024-12-31 | — | — | CN | disclosed |
| US-20230212144-A1 | 5-MEMBERED HETEROARYL DERIVATIVE CONTAINING AT LEAST ONE N, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDERS, CONTAINING SAME AS ACTIVE INGREDIENT | TRINEURO (KR) | 2023-07-06 | — | — | US | disclosed |
| CN-116057053-A | 5-membered heteroaryl derivatives containing at least one N and pharmaceutical compositions containing the same as active ingredient for preventing or treating mental disorders | 大邱庆北尖端医疗产业振兴财团 | 2023-05-02 | — | — | CN | disclosed |
| WO-2021241982-A1 | 5-MEMBERED HETEROARYL DERIVATIVE CONTAINING AT LEAST ONE N, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDERS, CONTAINING SAME AS ACTIVE INGREDIENT | 재단법인 대구경북첨단의료산업진흥재단 | 2021-12-02 | — | — | WO | disclosed |
| US-11078196-B2 | Heteroaryl amides as inhibitors of protein aggregation | UCB Biophama SRL (BE) | 2021-08-03 | — | — | US | disclosed |
| EP-3348556-B1 | HETEROARYL AMIDES AS INHIBITORS OF PROTEIN AGGREGATION | UCB Biopharma SRL (BE) | 2020-04-29 | — | — | EP | disclosed |
| US-20190308965-A1 | HETEROARYL AMIDES AS INHIBITORS OF PROTEIN AGGREGATION | UCB BIOPHARMA SPRL (BE) | 2019-10-10 | — | — | US | disclosed |
| US-10358443-B2 | Heteroaryl amides as inhibitors of protein aggregation | UCB BIOPHARMA SPRL (BE) | 2019-07-23 | — | — | US | disclosed |
| US-9738635-B2 | Heteroaryl amides as inhibitors of protein aggregation | NEUROPORE THERAPIES, INC. (US) | 2017-08-22 | — | — | US | disclosed |
| US-20160207912-A1 | HETEROARYL AMIDES AS INHIBITORS OF PROTEIN AGGREGATION | UCB BIOPHARMA SPRL (BE) | 2016-07-21 | — | — | US | disclosed |
| US-20080139535-A1 | INHIBITORS OF HISTONE DEACETYLASE | MIIKANA THERAPEUTICS | 2008-06-12 | — | — | US | disclosed |
| US-20080139535-A1 | INHIBITORS OF HISTONE DEACETYLASE | MIIKANA THERAPEUTICS | 2008-06-12 | — | — | US | disclosed |
| US-20080139535-A1 | INHIBITORS OF HISTONE DEACETYLASE | MIIKANA THERAPEUTICS | 2008-06-12 | — | — | US | disclosed |
| US-7345043-B2 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS (US) | 2008-03-18 | — | — | US | disclosed |
| US-7345043-B2 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS (US) | 2008-03-18 | — | — | US | disclosed |
| US-7345043-B2 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS (US) | 2008-03-18 | — | — | US | disclosed |
| EP-1755601-A2 | INHIBITORS OF HISTONE DEACETYLASE | Miikana Therapeutics, Inc. (US) | 2007-02-28 | — | — | EP | disclosed |
| US-20050250784-A1 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS CORPORATION | 2005-11-10 | — | — | US | disclosed |
| US-20050234033-A1 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS | 2005-10-20 | — | — | US | disclosed |
| WO-2005086898-A2 | INHIBITORS OF HISTONE DEACETYLASE | MIIKANA THERAPEUTICS, INC. (US) | 2005-09-22 | — | — | WO | disclosed |