Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 13/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 13/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 13/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 13/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 13/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 13/20 | 0.46 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12907952 | 1.00 | KIT (0.48) | KITPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6855102 | 0.82 | PSEN1 (0.67) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL24913716 | 0.79 | KIT (0.46) | KITROCK2ROCK1MEN1KMT2A | |
| SCHEMBL12944062 | 0.79 | ROCK2 (0.51) | KITROCK2ROCK1MEN1KMT2A | |
| SCHEMBL12943942 | 0.76 | KIT (0.49) | KITROCK2MEN1KMT2A | |
| SCHEMBL12944288 | 0.73 | KIT (0.48) | KIT | |
| SCHEMBL12943967 | 0.72 | ROCK2 (0.49) | KITPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12943969 | 0.72 | KIT (0.53) | KIT | |
| SCHEMBL12944610 | 0.71 | KIT (0.53) | KIT | |
| SCHEMBL12944259 | 0.71 | KIT (0.38) | KITROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230029372-A1 | THERAPEUTIC COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF DIASTOLIC DYSFUNCTION | Ambetex Pty Ltd (AU) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230029372-A1 | THERAPEUTIC COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF DIASTOLIC DYSFUNCTION | TNNI3, TNNT2, TNNC1 | KIT 4153/4885PSEN1 15/4885PSEN2 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.