SCHEMBL2491376

SCHEMBL2491376

CC(C)c1cc[c]c2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
CYP1A2 P05177 2/20 0.32
FAAH O00519 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
HTR2B P41595 1/20 0.32
GABRA2 P47869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8312100 0.86 GABRA1 (0.40) GABRA1GABRB2CYP1A2FAAHCA1
SCHEMBL7833543 0.81 TSHR (0.44) TSHRHTR2CHTR2B
SCHEMBL2456781 0.81 MEN1 (0.38)
SCHEMBL20563154 0.79
SCHEMBL15270642 0.77 UGT2B7 (0.35) GABRA1GABRB2CYP1A2LMNACYP3A4
SCHEMBL9506297 0.77 MPO (0.33)
SCHEMBL2464439 0.77 PGR (0.33)
SCHEMBL67474 0.73 CYP1A2 (0.50) CYP1A2LMNAHPGDTSHR
SCHEMBL8781825 0.71 GABRA1 (0.48) GABRA1GABRB2CYP1A2FAAHCA1
SCHEMBL30876294 0.71 GABRA1 (0.48) GABRA1GABRB2CYP1A2FAAHCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103571419-B Frame sealing adhesive for multi-dimensional electric field mode liquid crystal display panel and manufacture method of frame sealing adhesive BEIJING BOE OPTOELECTRONICS 2015-04-29 CN claimed
CN-103571419-A Frame sealing adhesive for multi-dimensional electric field mode liquid crystal display panel and manufacture method of frame sealing adhesive BOE TECHNOLOGY GROUP CO LTD 2014-02-12 CN claimed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US claimed
CN-104761533-B 1 hetero atom diene derivatives and noxious organism control agent 日本曹达株式会社 2017-12-05 CN disclosed
CN-107085033-A N phenylnaphthalenes aminated compounds as MALDI matrix application 中国科学院化学研究所 2017-08-22 CN disclosed
CN-102245571-B 1-heteroatom diene derivative and pest control agent NIPPON SODA CO.,LTD. (JP) 2015-07-29 CN disclosed
CN-104761533-A 1-heterodiene derivative and harmful organism control agent NIPPON SODA CO 2015-07-08 CN disclosed
CN-103571419-B Frame sealing adhesive for multi-dimensional electric field mode liquid crystal display panel and manufacture method of frame sealing adhesive BEIJING BOE OPTOELECTRONICS 2015-04-29 CN disclosed
EP-2380876-B1 1-HETERODIENE DERIVATIVE AND HARMFUL ORGANISM CONTROL AGENT NIPPON SODA CO (JP) 2014-10-29 EP disclosed
CN-103571419-A Frame sealing adhesive for multi-dimensional electric field mode liquid crystal display panel and manufacture method of frame sealing adhesive BOE TECHNOLOGY GROUP CO LTD 2014-02-12 CN disclosed
US-8222430-B2 1-heterodiene derivative and harmful organism control agent NIPPON SODA CO., LTD. (JP) 2012-07-17 US disclosed
US-5739345-A HYPOGLYCEMIC AND ANTIDIABETIC AGENTS SANKYO COMPANY, LIMITED (JP) 1998-04-14 US disclosed
CN-1157288-A Benzimidazole derivatives, their preparation and their therapeutic use SANKYO CO (JP) 1997-08-20 CN disclosed
US-5624935-A ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS SANKYO COMPANY, LIMITED 1997-04-29 US disclosed
EP-0745600-A1 Benzimidazole derivatives, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1996-12-04 EP disclosed
CN-1118781-A Heterocyclic compound with activity against diabetes and preparation and application of same MITSUTAKA CO LTD (JP) 1996-03-20 CN disclosed
EP-0676398-A2 Heterocyclic compounds having anti-diabetic activity, their preparation and their use SANKYO COMPANY LIMITED (JP) 1995-10-11 EP disclosed
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-4238613-A IMPARTING PHOTOSTABILITY AND OXIDATION AND HEAT RESISTANCE TO PLASTICS CIBA-GEIGY CORPORATION (US) 1980-12-09 US disclosed