Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 9/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 5/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30156653 | 1.00 | TRAP1 (0.41) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL24913857 | 0.91 | PTGDR2 (0.42) | SPRL3MBTL1ABCB1ABCG2RXRB | |
| SCHEMBL24913881 | 0.89 | TRAP1 (0.51) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL30156809 | 0.89 | TRAP1 (0.51) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL30368420 | 0.88 | SPR (0.49) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL25668954 | 0.88 | SPR (0.49) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL24913931 | 0.88 | TRAP1 (0.40) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL30156544 | 0.88 | TRAP1 (0.40) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL30156871 | 0.87 | TRAP1 (0.39) | TRAP1HSP90B1SPRHSP90AA1HSP90AB1 | |
| SCHEMBL30368285 | 0.87 | TRAP1 (0.54) | TRAP1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094834-A1 | ISOINDOLINES AS PMS2 INHIBITORS | Neophore Limited (GB) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023002165-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2023-01-26 | — | — | WO | disclosed |