Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 4/20 | 0.51 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24913881 | 1.00 | TRAP1 (0.51) | TRAP1HSP90B1ABHD6HSP90AA1ALDH1A1 | |
| SCHEMBL30368420 | 0.89 | SPR (0.49) | TRAP1HSP90B1HSP90AA1MAPTSPR | |
| SCHEMBL25668954 | 0.89 | SPR (0.49) | TRAP1HSP90B1HSP90AA1MAPTSPR | |
| SCHEMBL30156653 | 0.89 | TRAP1 (0.41) | TRAP1HSP90B1HSP90AA1SPRHSP90AB1 | |
| SCHEMBL24913845 | 0.89 | TRAP1 (0.41) | TRAP1HSP90B1HSP90AA1SPRHSP90AB1 | |
| SCHEMBL30368285 | 0.88 | TRAP1 (0.54) | TRAP1HSP90B1ABHD6ALDH1A1MEN1 | |
| SCHEMBL25668982 | 0.88 | TRAP1 (0.54) | TRAP1HSP90B1ABHD6ALDH1A1MEN1 | |
| SCHEMBL24913883 | 0.87 | SLC6A9 (0.40) | TRAP1HSP90B1HSP90AA1ALDH1A1SPR | |
| SCHEMBL24913931 | 0.87 | TRAP1 (0.40) | TRAP1HSP90B1HSP90AA1SPRHSP90AB1 | |
| SCHEMBL30156544 | 0.87 | TRAP1 (0.40) | TRAP1HSP90B1HSP90AA1SPRHSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240293392-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2024-09-05 | — | — | US | disclosed |
| CN-117693507-A | Inhibitor compounds | 奈奥芬莱有限公司 | 2024-03-12 | — | — | CN | disclosed |
| WO-2023002165-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2023-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240293392-A1 | INHIBITOR COMPOUNDS | MSH2, PMS2, MSH6 | TRAP1 1853/4885HSP90B1 1422/4885ABHD6 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.